Cardinals vs Pirates Picks, Odds & Starting Pitchers (June 4)

St. Louis is a -150 moneyline favorite in the Cardinals vs Pirates odds on Sunday morning The Pirates enter play riding a four-game winning streak Don’t miss the latest Cardinals vs Pirates picks, odds, and starting pitchers below Sunday mornings are usually reserved for sleeping in and brunch. Well, you...

April 16, 2026 • 10:22 AM

St. Louis is a -150 moneyline favorite in the Cardinals vs Pirates odds on Sunday morning

The Pirates enter play riding a four-game winning streak

Don’t miss the latest Cardinals vs Pirates picks, odds, and starting pitchers below

Sunday mornings are usually reserved for sleeping in and brunch. Well, you can now add a little MLB action to your Sunday morning ritual.

Peacock’s MLB Leadoff package is showcasing an 11:35 am ET contest nearly every Sunday morning until early September, with the Cardinals and Pirates having the honor of an early start this weekend.

Pittsburgh has taken the first two games of this three-game set, but online sportsbooks are siding against them in the MLB odds. They’ve pegged St. Louis as the road chalk for this matchup, despite some truly horrendous recent form.

Cardinals vs Pirates Odds

Team Moneyline Runline Total
St. Louis Cardinals -150 -1.5 (+105) O 9 (-115)
Pittsburgh Pirates +130 +1.5 (-125) U 9 (-105)

The Cardinals are currently -150 moneyline favorites, in a contest with a total of 9. PNC Park will play host to the contest, with clear skies and 68-degree game-time temperatures on deck.

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