World #2 Iga Swiatek is a massive favorite over #8 Amanda Anisimova on Wednesday
The pair have faced off just once before with Swiatek double-bageling the American earlier this season
See the Anisimova vs Swiatek odds, picks, and predictions for the US Open quarterfinal
Riding a ten-match win streak, world #2 Iga Swiatek meets 24-year-old American Amanda Anisimova in the quarterfinals of the 2025 US Open on Wednesday afternoon. The won’t start before 1:10 pm ET on Arthur Ashe, and the exact start time will depend on the length of the preceding matches.
Right now, there is little doubt that the Polish star is the favorite here. Swiatek has not overtaken Sabalenka in the odds to win the US Open after round four but it is drawing closer.
Anisimova vs Swiatek Odds
| Market | Anisimova | Swiatek |
|---|---|---|
| Moneyline | +300 at bet365 | -380 at Caesars |
| Game Spread | +4.5 (-110) at ESPN Bet | -4.5 (-115) at Caesars |
| Total Games | O 20.5 (-112) at FanDuel | U 20.5 (-110) at bet365 |
The best odds bettors are going to get on a Swiatek win are -380 at Caesars. Anisimova’s longest price is +300 at bet365. The game spread has been set at Swiatek -4.5; her best price to cover is -115 at Caesars, while Anisimova’s is -110 at ESPN Bet or DraftKings. The default game total is right at 20.5 games currently. FanDuel has the best over price (-112) and bet365 has the best under price (-110).
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